Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.43 |
| ▸ | CFD | P00746 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | CLK3 | P49761 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13104199 | 0.92 | F10 (0.47) | F10CFDNPC1RAB9ACYP2C9 | |
| SCHEMBL12101351 | 0.92 | F10 (0.47) | F10CFDNPC1RAB9ACYP2C9 | |
| SCHEMBL8222128 | 0.91 | F10 (0.43) | F10CFDHCRTR1HCRTR2TSHR | |
| SCHEMBL13104224 | 0.91 | F10 (0.46) | F10CFDHCRTR1HCRTR2NPC1 | |
| SCHEMBL8224896 | 0.91 | F10 (0.46) | F10CFDHCRTR1HCRTR2NPC1 | |
| SCHEMBL12101291 | 0.91 | F10 (0.52) | F10CFDHCRTR1HCRTR2TSHR | |
| SCHEMBL12101392 | 0.91 | F10 (0.43) | F10CFDHCRTR1HCRTR2TSHR | |
| SCHEMBL12892314 | 0.91 | F10 (0.43) | F10CFDHCRTR1HCRTR2TSHR | |
| SCHEMBL13104152 | 0.91 | F10 (0.52) | F10CFDHCRTR1HCRTR2TSHR | |
| SCHEMBL12101321 | 0.90 | F10 (0.44) | F10CFDHCRTR1HCRTR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051975-B1 | SUBSTITUTED PROLINAMIDES, PRODUCTION THEREOF AND THEIR USE AS DRUGS | BOEHRINGER INGELHEIM INT (DE) | 2012-09-12 | — | — | EP | disclosed |