SCHEMBL12109014

SCHEMBL12109014

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nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ NANP Q8TBE9 3/20 0.53
▸ NEU1 Q99519 2/20 0.49
▸ NEU3 Q9UQ49 2/20 0.41
▸ CD22 P20273 2/20 0.41
▸ NEU4 Q8WWR8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14275077 1.00 NANP (0.53) NANPNEU1NEU3CD22NEU4
SCHEMBL13895438 0.88 NANP (0.54) NANPNEU1NEU3NEU4
SCHEMBL20306037 0.88 NANP (0.54) NANPNEU1NEU3NEU4
SCHEMBL2742891 0.88 NANP (0.54) NANPNEU1NEU3NEU4
SCHEMBL23635227 0.88 NANP (0.54) NANPNEU1NEU3NEU4
SCHEMBL23640238 0.88 NANP (0.54) NANPNEU1NEU3NEU4
SCHEMBL13895451 0.88 NANP (0.54) NANPNEU1NEU3NEU4
SCHEMBL13703566 0.88 NEU1 (0.55) NANPNEU1NEU3CD22NEU4
SCHEMBL15147281 0.86 NANP (0.55) NANPCD22
SCHEMBL29576105 0.86 NANP (0.70) NANPNEU1NEU3CD22NEU4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8053410-B2 Pegylated factor VII glycoforms NOVO NORDISK HEALTH CARE A/G (CH) 2011-11-08 — — US disclosed
US-20090227504-A1 Pegylated Factor VII Glycoforms NOVO NORDISK A/S (DK) 2009-09-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090227504-A1 Pegylated Factor VII Glycoforms F7, F13B, F5 NANP 247/4885NEU1 62/4885NEU3 51/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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