Fesoterodine

Fesoterodine

SCHEMBL121127

CC(C)C(=O)Oc1ccc(CO)cc1[C@H](CCN(C(C)C)C(C)C)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CHRM2CHRM3

The experimentally established mechanism targets of Fesoterodine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 4/20 1.00
CHRM3 known ✓ P20309 11/20 0.46
CHRM1 P11229 4/20 1.00
MAPT P10636 4/20 0.46
LMNA P02545 3/20 0.46
CHRM5 P08912 2/20 0.46
HRH1 P35367 2/20 0.46
ADRA1A P35348 2/20 0.46
ESR1 P03372 1/20 0.46
CHRM4 P08173 1/20 0.46
KCNE1 P15382 1/20 0.46
PTGS1 P23219 1/20 0.46
HRH2 P25021 1/20 0.46
HTR2A P28223 1/20 0.46
SLC6A4 P31645 1/20 0.46
OPRK1 P41145 1/20 0.46
KCNQ1 P51787 1/20 0.46
KCNH2 Q12809 1/20 0.46
CACNA1C Q13936 1/20 0.46
SCN5A Q14524 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fesoterodine SCHEMBL29366015 1.00 CHRM2 (1.00) CHRM2CHRM1CHRM3MAPTLMNA
Fesoterodine SCHEMBL1808421 1.00 CHRM2 (1.00) CHRM2CHRM1CHRM3MAPTLMNA
Fesoterodine SCHEMBL812986 1.00 CHRM2 (1.00) CHRM2CHRM1CHRM3MAPTLMNA
Fesoterodine SCHEMBL15148766 1.00 CHRM2 (1.00) CHRM2CHRM1CHRM3MAPTLMNA
Fesoterodine SCHEMBL3688110 0.99 CHRM2 (0.98) CHRM2CHRM1CHRM3MAPTLMNA
Fesoterodine SCHEMBL2474276 0.99 CHRM2 (0.98) CHRM2CHRM1CHRM3MAPTLMNA
Fesoterodine SCHEMBL2474910 0.98 CHRM2 (0.96) CHRM2CHRM1CHRM3MAPTLMNA
Fesoterodine SCHEMBL2474905 0.98 CHRM2 (0.96) CHRM2CHRM1CHRM3MAPTLMNA
Fesoterodine SCHEMBL814971 0.95 CHRM2 (0.90) CHRM2CHRM1CHRM3MAPTLMNA
Fesoterodine SCHEMBL1993629 0.95 CHRM2 (0.90) CHRM2CHRM1CHRM3MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2985 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12638459-B2 Method of diagnosing overactive bladder disorder UNIVERSITY OF PORTSMOUTH HIGHER EDUCATION CORPORATION (GB) 2026-05-26 US claimed
WO-2026100654-A1 NUCLEIC ACID INTRODUCTION AID, NUCLEIC ACID INTRODUCTION AGENT, AND NUCLEIC ACID INTRODUCTION METHOD 株式会社インファーマシア 2026-05-15 WO claimed
EP-4736841-A1 A MUCOADHESIVE LAYER FOR BUCCAL ADMINISTRATION OF AN ACTIVE PHARMACEUTICAL INGREDIENT IQ medical GmbH (DE) 2026-05-06 EP claimed
EP-4719383-A2 COMPOSITIONS FOR TREATING NEUROLOGICAL DISORDERS MapLight Therapeutics, Inc. (US) 2026-04-08 EP claimed
EP-3731931-B1 MODIFIED RELEASE FORMULATIONS OF FESOTERODINE SANOVEL ILAC SANAYI VE TICARET AS (TR) 2025-11-26 EP claimed
US-20250302814-A1 METHODS AND COMPOSITIONS FOR TREATING SLEEP APNEA APNIMED, INC. (DELAWARE) 2025-10-02 US claimed
US-12427119-B2 Transdermal delivery system including an interface mediator LTS LOHMANN THERAPIE-SYSTEME AG (DE) 2025-09-30 US claimed
US-20250275924-A1 Anticholinergic Agents and Muscarinic Agonists for the Treatment of Demodex Related Conditions ATTILLAPS HOLDINGS INC. 2025-09-04 US claimed
US-20250241933-A1 METHODS OF TREATING SLEEP APNEA WITH A COMBINATION OF A CANNABINOID AND A CARBONIC ANHYDRASE INHIBITOR APNIMED, INC. (DELAWARE) 2025-07-31 US claimed
US-20250228832-A1 METHODS FOR TREATING DISORDERS AMELIORATED BY MUSCARINIC RECEPTOR ACTIVATION Karuna Therapeutics, Inc. 2025-07-17 US claimed
US-20050137194-A1 Combination of selected opioids with other active compounds for treatment of urinary incontinence GRUENENTHAL GMBH (DE) 2005-06-23 US claimed
US-20050107349-A1 Method for the treatment or prevention of respiratory disorders with a cyclooxygenase-2 inhibitor in combination with a muscarinic receptor antagonist and compositions therewith PHARMACIA CORPORATION (US) 2005-05-19 US claimed
WO-2004089872-A1 HIGHLY PURE BASES OF 3,3-DIPHENYL PROPYLAMINE MONOESTERS SCHWARZ PHARMA AG (DE) 2004-10-21 WO claimed
US-20040186061-A1 Novel derivatives of 3,3-diphenylpropylamines SCHWARZ PHARMA AG 2004-09-23 US claimed
US-6713464-B1 ANTIMUSCARINIC AGENTS WITH SUPERIOR PHARMACOKINETICS SCHWARZ PHARMA AG (DE) 2004-03-30 US claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
EP-1254890-A1 Derivatives of 3,3-diphenylpropylamines SCHWARZ PHARMA AG (DE) 2002-11-06 EP claimed
EP-1077912-B1 NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES SANOL ARZNEI SCHWARZ GMBH (DE) 2002-07-03 EP claimed
EP-1077912-A1 NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES SCHWARZ PHARMA AG (DE) 2001-02-28 EP claimed
WO-1999058478-A1 NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES SCHWARZ PHARMA AG (DE) 1999-11-18 WO claimed