Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.62 |
| ▸ | S1PR5 | Q9H228 | 8/20 | 0.62 |
| ▸ | S1PR4 | O95977 | 7/20 | 0.62 |
| ▸ | S1PR3 | Q99500 | 10/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1336443 | 0.90 | S1PR1 (0.67) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL1336266 | 0.89 | S1PR1 (0.64) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL1336650 | 0.89 | S1PR1 (0.67) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL1335722 | 0.88 | S1PR1 (0.62) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL1335612 | 0.87 | S1PR1 (0.64) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL12129286 | 0.83 | S1PR1 (0.43) | S1PR1S1PR3 | |
| SCHEMBL1335945 | 0.81 | S1PR1 (0.68) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL14237186 | 0.80 | S1PR1 (0.54) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL14237139 | 0.80 | S1PR1 (0.52) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL1334297 | 0.80 | S1PR1 (0.67) | S1PR1S1PR5S1PR4S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389509-B2 | Substituted pyrazole compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-03-05 | — | — | US | disclosed |
| US-20110275610-A1 | SUBSTITUTED PYRAZOLE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275610-A1 | SUBSTITUTED PYRAZOLE COMPOUNDS | S1PR3, S1PR1, S1PR4 | S1PR1 2/4885S1PR5 4/4885S1PR4 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.