Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.33 |
| ▸ | CPT2 | P23786 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12138705 | 0.99 | ACACB (0.44) | ACACBACACAFFAR1FFAR4GPR84 | |
| SCHEMBL5902817 | 0.89 | FFAR1 (0.47) | ACACBACACAFFAR1FFAR4GPR84 | |
| SCHEMBL1152115 | 0.88 | FFAR1 (0.50) | ACACBACACAFFAR1FFAR4GPR84 | |
| SCHEMBL5902930 | 0.88 | ACACB (0.41) | ACACBACACAFFAR1FFAR4CPT2 | |
| SCHEMBL5902992 | 0.87 | ACACB (0.43) | ACACBACACAFFAR1FFAR4GPR84 | |
| SCHEMBL14150077 | 0.86 | ACACB (0.47) | ACACBACACAFFAR1FFAR4GPR84 | |
| SCHEMBL2737107 | 0.86 | ACACB (0.39) | ACACBACACAFFAR1FFAR4CPT2 | |
| SCHEMBL1151589 | 0.85 | ACACB (0.41) | ACACBACACAFFAR1FFAR4GPR84 | |
| SCHEMBL1146226 | 0.84 | FFAR4 (0.39) | ACACBACACAFFAR1FFAR4GPR84 | |
| SCHEMBL2737156 | 0.83 | FFAR4 (0.41) | ACACBACACAFFAR1FFAR4GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067466-B2 | Cycloalkyl-hydroxyl compounds and compositions for cholesterol management | ESPERION THERAPEUTICS, INC. (US) | 2011-11-29 | — | — | US | disclosed |