⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578883 | 0.81 | — | — | |
| SCHEMBL19435448 | 0.62 | — | — | |
| SCHEMBL17621269 | 0.58 | — | — | |
| SCHEMBL12147304 | 0.56 | — | — | |
| SCHEMBL18405453 | 0.49 | — | — | |
| SCHEMBL12147354 | 0.47 | — | — | |
| SCHEMBL10538247 | 0.43 | — | — | |
| SCHEMBL2812676 | 0.41 | — | — | |
| SCHEMBL129646 | 0.36 | — | — | |
| SCHEMBL3953115 | 0.35 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3571187-B1 | CHEMICAL COMPOUNDS AS INHIBITORS OF INTERLEUKIN-1 ACTIVITY | GENENTECH INC (US) | 2023-11-22 | — | — | EP | disclosed |
| WO-2017079270-A1 | METHOD OF TREATING DISEASE BY AURICULAR ANESTHESIA OF CRANIAL NERVES | CREWS THOMAS M (US) | 2017-05-11 | — | — | WO | disclosed |
| US-9115136-B2 | Fused ring compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-08-25 | — | — | US | disclosed |
| US-8921379-B2 | Fused ring compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-12-30 | — | — | US | disclosed |
| US-20140046056-A1 | FUSED RING COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-02-13 | — | — | US | disclosed |
| US-8283353-B2 | Fused ring compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-10-09 | — | — | US | disclosed |
| US-20110294832-A1 | FUSED RING COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2011-12-01 | — | — | US | disclosed |
| US-20110288087-A1 | FUSED RING COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2011-11-24 | — | — | US | disclosed |
| US-7812044-B2 | Anticancer agents | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-10-12 | — | — | US | disclosed |
| US-20100197683-A1 | FUSED RING COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2010-08-05 | — | — | US | disclosed |
| US-20100120800-A1 | AGENT FOR PREVENTING RECURRENCE OF CEREBROVASCULAR DISORDER AND AGENT FOR AMELIORATING TROUBLES FOLLOWING CEREBROVASCULAR DISORDER AND INHIBITING PROGRESS THEREOF | OJIMA MAMI | 2010-05-13 | — | — | US | disclosed |
| US-7582662-B2 | Body weight gain inhibitor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-01 | — | — | US | disclosed |
| US-20080312435-A1 | Imine Compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-12-18 | — | — | US | disclosed |
| US-20080312435-A1 | Imine Compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-12-18 | — | — | US | disclosed |
| US-7378108-B1 | Percutaneous absorption preparation of compound having angiotensin II antagonistic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-27 | — | — | US | disclosed |
| US-7294344-B2 | Sustained-release preparation for AII antagonist, production and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-11-13 | — | — | US | disclosed |