Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 19/20 | 0.70 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12147448 | 0.94 | PTGDR2 (0.71) | PTGDR2AKR1B1PTGDR | |
| SCHEMBL12147550 | 0.91 | PTGDR2 (0.71) | PTGDR2AKR1B1PTGDR | |
| SCHEMBL12147356 | 0.90 | PTGDR2 (0.83) | PTGDR2AKR1B1PTGDR | |
| SCHEMBL12147332 | 0.88 | PTGDR2 (0.72) | PTGDR2AKR1B1PTGDR | |
| SCHEMBL12147175 | 0.86 | PTGDR2 (0.77) | PTGDR2 | |
| SCHEMBL12147457 | 0.86 | PTGDR2 (0.70) | PTGDR2AKR1B1PTGDR | |
| SCHEMBL12147073 | 0.85 | PTGDR2 (0.65) | PTGDR2AKR1B1PTGDR | |
| SCHEMBL12147165 | 0.85 | PTGDR2 (0.71) | PTGDR2AKR1B1PTGDR | |
| SCHEMBL12147145 | 0.84 | PTGDR2 (0.62) | PTGDR2AKR1B1PTGDR | |
| SCHEMBL12147163 | 0.83 | PTGDR2 (0.69) | PTGDR2AKR1B1PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273769-B2 | Phenoxy acetic acid derivatives | MERCK SERONO SA (CH) | 2012-09-25 | — | — | US | disclosed |
| US-20110288066-A1 | PHENOXY ACETIC ACID DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-11-24 | — | — | US | disclosed |
| WO-2010092043-A1 | PHENOXY ACETIC ACID DERIVATIVES | MERCK SERONO S.A. (CH) | 2010-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288066-A1 | PHENOXY ACETIC ACID DERIVATIVES | HRH2, HRH1, HRH3 | PTGDR2 51/4885AKR1B1 73/4885PTGDR 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.