Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12147649 | 0.90 | PTGDR2 (0.59) | PTGDR2KDM4ESMN1; SMN2 | |
| SCHEMBL2103451 | 0.84 | KDM4E (0.54) | PTGDR2KDM4ESMN1; SMN2 | |
| SCHEMBL1370745 | 0.83 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL12147278 | 0.81 | PTGDR2 (0.68) | PTGDR2 | |
| SCHEMBL12147509 | 0.79 | PTGDR2 (0.59) | PTGDR2KDM4ESMN1; SMN2 | |
| SCHEMBL12147312 | 0.79 | PTGDR2 (0.69) | PTGDR2 | |
| SCHEMBL12147076 | 0.77 | PTGDR2 (0.59) | PTGDR2KDM4ESMN1; SMN2 | |
| SCHEMBL12147090 | 0.77 | PTGDR2 (0.63) | PTGDR2 | |
| SCHEMBL12147463 | 0.76 | PTGDR2 (0.55) | PTGDR2 | |
| SCHEMBL2101453 | 0.76 | PTGDR2 (0.54) | PTGDR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273769-B2 | Phenoxy acetic acid derivatives | MERCK SERONO SA (CH) | 2012-09-25 | — | — | US | disclosed |
| US-20110288066-A1 | PHENOXY ACETIC ACID DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-11-24 | — | — | US | disclosed |
| WO-2010092043-A1 | PHENOXY ACETIC ACID DERIVATIVES | MERCK SERONO S.A. (CH) | 2010-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288066-A1 | PHENOXY ACETIC ACID DERIVATIVES | HRH2, HRH1, HRH3 | PTGDR2 51/4885KDM4E 1974/4885APEX1 4499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.