Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | GLP1R | P43220 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16329593 | 0.85 | GLP1R (0.45) | AKT1CA1CA2CAPN1SIRT5 | |
| SCHEMBL13647129 | 0.85 | AKT1 (0.51) | AKT1CA1CA2MEN1KMT2A | |
| SCHEMBL16329598 | 0.85 | GLP1R (0.45) | AKT1CA1CA2CAPN1GLP1R | |
| SCHEMBL26445412 | 0.85 | GLP1R (0.45) | AKT1CA1CA2CAPN1GLP1R | |
| SCHEMBL22025537 | 0.85 | GLP1R (0.45) | AKT1CA1CA2CAPN1GLP1R | |
| SCHEMBL19541913 | 0.85 | GLP1R (0.45) | AKT1CA1CA2CAPN1GLP1R | |
| SCHEMBL16329597 | 0.85 | GLP1R (0.45) | AKT1CA1CA2CAPN1GLP1R | |
| SCHEMBL16328767 | 0.84 | TLR2 (0.42) | AKT1CA1CA2GLP1R | |
| SCHEMBL15607620 | 0.84 | AKT1 (0.47) | AKT1CA1CA2MEN1KMT2A | |
| SCHEMBL22044586 | 0.84 | AKT1 (0.48) | AKT1CA1CA2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067005-B1 | Divalent antibody fragments | UCB PHARMA S.A. (BE) | 2011-11-29 | — | — | US | disclosed |