Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAE1 | Q13564 | 5/20 | 0.35 |
| ▸ | UBA3 | Q8TBC4 | 5/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12150570 | 0.89 | IRAK4 (0.38) | NAE1UBA3NFE2L2KMT2A | |
| SCHEMBL12150685 | 0.85 | IRAK4 (0.42) | — | |
| SCHEMBL12150694 | 0.79 | IRAK4 (0.40) | — | |
| SCHEMBL802894 | 0.76 | PDE10A (0.39) | NAE1UBA3 | |
| SCHEMBL802501 | 0.76 | PDE10A (0.39) | NAE1UBA3 | |
| SCHEMBL12150716 | 0.75 | IRAK4 (0.43) | — | |
| SCHEMBL12150673 | 0.75 | IRAK4 (0.43) | — | |
| SCHEMBL12150542 | 0.75 | IRAK4 (0.54) | — | |
| SCHEMBL12150681 | 0.70 | IRAK4 (0.39) | — | |
| SCHEMBL12150672 | 0.70 | IRAK4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110286965-A1 | ETHENYL-SUBSTITUTED PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS | MERCK SHARP & DOHME LLC | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110286965-A1 | ETHENYL-SUBSTITUTED PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS | CYP2C9, PNP, UGT1A3 | NAE1 719/4885UBA3 203/4885NFE2L2 2307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.