Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10326904 | 0.82 | CYP3A4 (0.34) | NOTUM | |
| SCHEMBL1733111 | 0.77 | NOTUM (0.33) | NOTUM | |
| SCHEMBL13411361 | 0.77 | CYP1A2 (0.38) | — | |
| SCHEMBL12151881 | 0.76 | NOTUM (0.33) | NOTUM | |
| SCHEMBL12528172 | 0.74 | CYP3A4 (0.34) | NOTUM | |
| SCHEMBL13909729 | 0.71 | KMT2A (0.32) | — | |
| SCHEMBL13909691 | 0.71 | CYP2A6 (0.38) | — | |
| SCHEMBL9286142 | 0.71 | CYP3A4 (0.39) | — | |
| Hydrochloric Acid SCHEMBL9284226 | 0.70 | CYP3A4 (0.39) | — | |
| SCHEMBL2628936 | 0.69 | NOTUM (0.41) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012142080-A1 | THIOAMIDE, AMIDOXIME AND AMIDRAZONE DERIVATIVES AS HIV ATTACHMENT INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-10-18 | — | — | WO | disclosed |
| EP-1943221-B1 | PIPERAZINE AMIDINES AS ANTIVIRAL AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2011-11-23 | — | — | EP | disclosed |
| US-7807671-B2 | Diketo-piperazine and piperidine derivatives as antiviral agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-10-05 | — | — | US | disclosed |