⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817145 | 0.82 | — | — | |
| SCHEMBL3862434 | 0.71 | — | — | |
| SCHEMBL7551468 | 0.71 | — | — | |
| SCHEMBL11491374 | 0.67 | — | — | |
| SCHEMBL4596033 | 0.66 | — | — | |
| SCHEMBL8815426 | 0.66 | — | — | |
| SCHEMBL8416616 | 0.65 | — | — | |
| SCHEMBL7554177 | 0.61 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL11172334 | 0.59 | — | — | |
| SCHEMBL3626475 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 914 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021079-A1 | NOX INHIBITORS FOR USE IN THE TREATMENT OF ALPORT SYNDROME | CALLIDITAS THERAPEUTICS SUISSE SA (CH) | 2026-01-22 | — | — | US | claimed |
| EP-4522162-A1 | NOX INHIBITORS FOR USE IN THE TREATMENT OF ALPORT SYNDROME | Calliditas Therapeutics Suisse SA (CH) | 2025-03-19 | — | — | EP | claimed |
| US-20250032462-A1 | BAX ACTIVATORS AND USES THEREOF IN CANCER THERAPY | ALBERT EINSTEIN COLLEGE MEDICINE (US) | 2025-01-30 | — | — | US | claimed |
| US-12016845-B2 | BAX activators and uses thereof in cancer therapy | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2024-06-25 | — | — | US | claimed |
| WO-2023217764-A1 | NOX INHIBITORS FOR USE IN THE TREATMENT OF ALPORT SYNDROME | CALLIDITAS THERAPEUTICS SUISSE SA (CH) | 2023-11-16 | — | — | WO | claimed |
| CN-115716805-A | Method for asymmetric catalytic synthesis of chiral pyrazolone derivative containing propargyl alcohol structural fragment | 重庆医科大学 | 2023-02-28 | — | — | CN | claimed |
| US-20220313665-A1 | BAX ACTIVATORS AND USES THEREOF IN CANCER THERAPY | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2022-10-06 | — | — | US | claimed |
| CN-113248549-A | Preparation method of rare earth-iridium-mixed metal complex soft salt | 西北大学 | 2021-08-13 | — | — | CN | claimed |
| US-20200093802-A1 | BAX ACTIVATORS AND USES THEREOF IN CANCER THERAPY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-03-26 | — | — | US | claimed |
| US-9572754-B2 | Transparent self-tanning gels containing a water-soluble/dispersible acrylamido-2-methylpropanesulfonic acid polymer | L'OREAL (FR) | 2017-02-21 | — | — | US | claimed |
| EP-0868906-A1 | Artificial tanning compositions | L'OREAL (FR) | 1998-10-07 | — | — | EP | claimed |
| WO-1997035842-A1 | COSMETIC COMPOSITIONS CONTAINING PYRAZOLIN-4,5-DIONES, NOVEL PYRAZOLIN-4,5-DIONES, PREPARATION METHODS THEREFOR AND USES THEREOF | L'OREAL (FR) | 1997-10-02 | — | — | WO | claimed |
| EP-0740200-A1 | Photographic elements containing oxonol filter dye mixture and their preparation | EASTMAN KODAK COMPANY (US) | 1996-10-30 | — | — | EP | claimed |
| US-5466813-A | Imine dye and photographic elements containing same | EASTMAN KODAK COMPANY (US) | 1995-11-14 | — | — | US | claimed |
| EP-0679939-A1 | Acyl substituted oxonol dyes | EASTMAN KODAK COMPANY (US) | 1995-11-02 | — | — | EP | claimed |
| US-5451494-A | Photographic elements containing acyl substituted oxonol dyes | EASTMAN KODAK COMPANY (US) | 1995-09-19 | — | — | US | claimed |
| US-5399690-A | Contain at least two nitrile groups, non-wandering | EASTMAN KODAK COMPANY (US) | 1995-03-21 | — | — | US | claimed |
| EP-0598420-A1 | Imine dyes and photographic elements containing same | EASTMAN KODAK COMPANY (US) | 1994-05-25 | — | — | EP | claimed |
| US-5260179-A | Containing a filter dye in a hydrophilic layer | EASTMAN KODAK COMPANY (US) | 1993-11-09 | — | — | US | claimed |
| US-4659732-A | Lipoxygenase inhibiting 1-arylalkyl-, 1-arylthio-, and 1-aryloxypyrazole-4,5-diones | BAYER AKTIENGESELLSCHAFT (DE) | 1987-04-21 | — | — | US | claimed |