Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.72 |
| ▸ | PDE11A | Q9HCR9 | 11/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13920197 | 0.92 | PDE4B (0.71) | PDE4BPDE11A | |
| SCHEMBL13920026 | 0.91 | PDE4B (0.79) | PDE4BPDE11A | |
| SCHEMBL13920254 | 0.90 | PDE4B (0.73) | PDE4BPDE11A | |
| SCHEMBL13920203 | 0.89 | PDE4B (0.68) | PDE4BPDE11A | |
| SCHEMBL8272918 | 0.89 | PDE4B (0.78) | PDE4BPDE11A | |
| SCHEMBL13919816 | 0.89 | PDE4B (0.78) | PDE4BPDE11A | |
| SCHEMBL13919826 | 0.89 | PDE4B (0.69) | PDE4BPDE11A | |
| SCHEMBL13919833 | 0.88 | PDE4B (0.75) | PDE4BPDE11A | |
| SCHEMBL13919414 | 0.88 | PDE4B (0.73) | PDE4BPDE11A | |
| SCHEMBL13919807 | 0.88 | PDE4B (0.90) | PDE4BPDE11A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758883-B1 | Substituted 2-quinolyl-oxazoles useful as PDE4 inhibitors | SCHERING CORP (US) | 2011-11-02 | — | — | EP | disclosed |