Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 11/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12163893 | 0.92 | ADORA1 (0.42) | ADORA1SLC6A3KDM4EMEN1ALDH1A1 | |
| SCHEMBL13938791 | 0.88 | ADORA1 (0.45) | ADORA1SLC6A3KDM4EMEN1KMT2A | |
| SCHEMBL10194492 | 0.88 | ADORA1 (0.54) | ADORA1SLC6A3KDM4EMEN1KMT2A | |
| SCHEMBL12553145 | 0.87 | ADORA1 (0.55) | ADORA1SLC6A3KDM4EMEN1ALDH1A1 | |
| SCHEMBL12163902 | 0.86 | ADORA1 (0.41) | ADORA1SLC6A3KDM4EMEN1ALDH1A1 | |
| SCHEMBL12164115 | 0.86 | ADORA1 (0.41) | ADORA1SLC6A3KDM4EMEN1ALDH1A1 | |
| SCHEMBL12163892 | 0.83 | NPSR1 (0.47) | ADORA1SLC6A3KDM4EMEN1ALDH1A1 | |
| SCHEMBL12163894 | 0.83 | ADORA1 (0.41) | ADORA1SLC6A3KDM4EMEN1ALDH1A1 | |
| SCHEMBL12164106 | 0.81 | ADORA1 (0.43) | ADORA1SLC6A3KDM4EMEN1ALDH1A1 | |
| SCHEMBL1930461 | 0.81 | ADORA1 (0.55) | ADORA1SLC6A3KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185550-B1 | SUBSTITUTED ARYLOXAZOLES AND THE USE THEREOF | Bayer Pharma AG (DE) | 2011-11-02 | — | — | EP | disclosed |