⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6426853 | 0.91 | — | — | |
| Methane SCHEMBL27461467 | 0.91 | — | — | |
| Methane SCHEMBL28135698 | 0.91 | — | — | |
| SCHEMBL298978 | 0.91 | — | — | |
| Methane SCHEMBL725158 | 0.91 | — | — | |
| SCHEMBL6425633 | 0.91 | — | — | |
| Methane SCHEMBL7738431 | 0.83 | — | — | |
| Methane SCHEMBL7853 | 0.83 | — | — | |
| SCHEMBL20337841 | 0.83 | — | — | |
| Methane SCHEMBL22122451 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 417 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903532-A | Preparation method of roflumilast | 珠海优润医药科技有限公司 | 2023-10-20 | — | — | CN | claimed |
| CN-112679429-B | Method for preparing isoquinolinones compound | 上海迪赛诺化学制药有限公司 | 2023-05-05 | — | — | CN | claimed |
| CN-112679430-B | Method for preparing isoquinolinones compound | 上海迪赛诺化学制药有限公司 | 2023-05-05 | — | — | CN | claimed |
| US-20230112619-A1 | METHOD FOR PREPARING ISOQUINOLINONE COMPOUNDS | ARIZEST (SHANGHAI) PHARMATECH CO., LTD. (CN) | 2023-04-13 | — | — | US | claimed |
| CN-112574234-B | Preparation method of ecteinascidin derivative | 江苏恒瑞医药股份有限公司 | 2022-05-24 | — | — | CN | claimed |
| CN-112679429-A | Method for preparing isoquinolone compound | 上海迪赛诺化学制药有限公司 | 2021-04-20 | — | — | CN | claimed |
| CN-112679430-A | Method for preparing isoquinolone compound | 上海迪赛诺化学制药有限公司 | 2021-04-20 | — | — | CN | claimed |
| CN-112574234-A | Preparation method of ecteinascidin derivative | 江苏恒瑞医药股份有限公司 | 2021-03-30 | — | — | CN | claimed |
| CN-110903242-A | Preparation method of intermediate of roxasistat | 天津科伦药物研究有限公司 | 2020-03-24 | — | — | CN | claimed |
| US-9550940-B2 | Etching material | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2017-01-24 | — | — | US | claimed |
| US-20150299568-A1 | ETCHING MATERIAL | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2015-10-22 | — | — | US | claimed |
| CN-117062813-B | Polycyclic compound and application thereof | 四川汇宇制药股份有限公司 | 2026-05-19 | — | — | CN | disclosed |
| EP-4725946-A1 | IRAK4 DEGRADATION AGENT AND USE THEREOF | Guangzhou Unirise Pharmaceutical Co., Ltd. (CN) | 2026-04-15 | — | — | EP | disclosed |
| EP-4384523-B1 | 2,2-DIFLUORO-5H-[1,3]DIOXOLO[4,5-F]ISOINDOL-7-ONE DERIVATIVES AS PESTICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2026-04-08 | — | — | EP | disclosed |
| US-12595266-B2 | Pesticidally active heterocyclic derivatives with sulfur containing substituents | SYNGENTA CROP PROTECTION AG (CH) | 2026-04-07 | — | — | US | disclosed |
| US-20100137323-A1 | BENZO-FUSED COMPOUNDS FOR USE IN TREATING METABOLIC DISORDERS | AMGEN INC. (US) | 2010-06-03 | — | — | US | disclosed |
| US-7687526-B2 | Benzo-fused compounds for use in treating metabolic disorders | AMGEN INC. (US) | 2010-03-30 | — | — | US | disclosed |
| EP-2061760-A1 | BENZO-FUSED COMPOUNDS FOR USE IN TREATING METABOLIC DISORDERS | Amgen, Inc (US) | 2009-05-27 | — | — | EP | disclosed |
| US-20080119511-A1 | Benzo-fused compounds for use in treating metabolic disorders | AMGEN INC. (US) | 2008-05-22 | — | — | US | disclosed |
| WO-2008030618-A1 | BENZO-FUSED COMPOUNDS FOR USE IN TREATING METABOLIC DISORDERS | AMGEN INC. (US) | 2008-03-13 | — | — | WO | disclosed |