Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12167663 | 0.84 | MAPT (0.42) | MAPTMAPK1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL12167534 | 0.83 | TRPV1 (0.47) | KDM4EALDH1A1HSD17B10TSHRMEN1 | |
| SCHEMBL14546905 | 0.77 | KCNH2 (0.43) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL2553893 | 0.76 | HPGD (0.42) | SCN10AKDM4EMAPTMAPK1ALDH1A1 | |
| SCHEMBL12167529 | 0.76 | TRPV1 (0.40) | KDM4ETRPV1 | |
| SCHEMBL2553309 | 0.76 | TRPV1 (0.47) | SCN10ATRPV1 | |
| SCHEMBL15831847 | 0.74 | CYP1A2 (0.41) | SCN10AKDM4EMAPTMAPK1ALDH1A1 | |
| SCHEMBL14534297 | 0.74 | KDM4E (0.36) | KDM4EMAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL2555362 | 0.74 | TRPV1 (0.47) | TRPV1 | |
| SCHEMBL2529549 | 0.74 | TRPV1 (0.43) | MAPK1TRPV1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2388258-A1 | Novel vanilloid receptor ligands and their use for producing medicaments | Grünenthal GmbH (DE) | 2011-11-23 | — | — | EP | disclosed |