⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10157463 | 0.77 | — | — | |
| SCHEMBL15555890 | 0.61 | — | — | |
| SCHEMBL12121211 | 0.60 | DYRK1A (0.46) | — | |
| SCHEMBL12181145 | 0.60 | — | — | |
| SCHEMBL15334769 | 0.60 | DYRK1A (0.46) | — | |
| SCHEMBL22339498 | 0.60 | — | — | |
| SCHEMBL8480586 | 0.60 | DYRK1A (0.52) | — | |
| SCHEMBL600914 | 0.60 | — | — | |
| SCHEMBL4039141 | 0.60 | — | — | |
| SCHEMBL4654506 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011145035-A1 | NOVEL 3,5-DISUBSTITUED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUED -3H-[1,2,3]TRIAZOLO[4,5-B] PYRIDINE COMPOUNDS AS MODULATORS OF PROTEIN KINASES | INDIAN INCOZEN THERAPEUTICS PVT. LTD. (IN) | 2011-11-24 | — | — | WO | disclosed |