Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SSTR5 | P35346 | 5/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12184387 | 0.94 | KCNH2 (0.48) | KCNH2CACNA1GOPRL1HIF1AEPAS1 | |
| SCHEMBL12184456 | 0.93 | KCNH2 (0.47) | KCNH2CACNA1GOPRL1POLBHIF1A | |
| SCHEMBL12184369 | 0.92 | DRD4 (0.53) | KCNH2MEN1KMT2A | |
| SCHEMBL12185020 | 0.91 | KCNH2 (0.45) | KCNH2CACNA1GOPRL1POLBSSTR5 | |
| SCHEMBL12184479 | 0.90 | SSTR5 (0.45) | KCNH2CACNA1GOPRL1POLBSSTR5 | |
| SCHEMBL12184576 | 0.89 | KCNH2 (0.55) | KCNH2CACNA1GOPRL1POLBSSTR5 | |
| SCHEMBL12184611 | 0.89 | SSTR5 (0.46) | KCNH2OPRL1POLBSSTR5HIF1A | |
| SCHEMBL12185032 | 0.89 | MEN1 (0.51) | KCNH2CACNA1GOPRL1SSTR5LMNA | |
| SCHEMBL12184423 | 0.89 | HIF1A (0.46) | KCNH2CACNA1GOPRL1POLBSSTR5 | |
| SCHEMBL12184865 | 0.88 | KMT2A (0.55) | KCNH2CACNA1GOPRL1SSTR5HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011142359-A1 | SPIRO COMPOUND AND DRUG FOR ACTIVATING ADIPONECTIN RECEPTOR | 日産化学工業株式会社 (JP) | 2011-11-17 | — | — | WO | disclosed |