Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SSTR5 | P35346 | 4/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | EBP | Q15125 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12184386 | 0.90 | SLC2A1 (0.42) | GRM2KDM4EALDH1A1SSTR5SLC2A1 | |
| SCHEMBL12184753 | 0.89 | SLC2A1 (0.42) | GRM2KDM4EALDH1A1SSTR5SLC2A1 | |
| SCHEMBL12184508 | 0.88 | SLC2A1 (0.46) | KDM4EALDH1A1SSTR5SLC2A1OPRL1 | |
| SCHEMBL12185054 | 0.88 | SLC2A1 (0.46) | KDM4EALDH1A1SSTR5SLC2A1OPRL1 | |
| SCHEMBL12184424 | 0.87 | ACKR3 (0.48) | SSTR5SIGMAR1 | |
| SCHEMBL12184554 | 0.84 | KCNH2 (0.43) | SSTR5SLC2A1OPRL1SIGMAR1FFAR1 | |
| SCHEMBL12184490 | 0.84 | OPRL1 (0.42) | SSTR5SLC2A1OPRL1SIGMAR1FFAR1 | |
| SCHEMBL12185022 | 0.84 | KCNH2 (0.43) | SSTR5SLC2A1OPRL1SIGMAR1FFAR1 | |
| SCHEMBL12184960 | 0.84 | DRD4 (0.51) | KDM4ESSTR5SIGMAR1 | |
| SCHEMBL12184674 | 0.84 | SLC2A1 (0.39) | GRM2SSTR5SLC2A1SIGMAR1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011142359-A1 | SPIRO COMPOUND AND DRUG FOR ACTIVATING ADIPONECTIN RECEPTOR | 日産化学工業株式会社 (JP) | 2011-11-17 | — | — | WO | disclosed |