Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 19/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2593310 | 0.87 | CHEK1 (1.00) | CHEK1 | |
| SCHEMBL12184801 | 0.85 | CHEK1 (0.76) | CHEK1 | |
| SCHEMBL12184776 | 0.80 | CHEK1 (0.72) | CHEK1 | |
| SCHEMBL12184777 | 0.80 | CHEK1 (0.76) | CHEK1 | |
| SCHEMBL12184648 | 0.78 | CHEK1 (0.75) | CHEK1 | |
| SCHEMBL12184666 | 0.78 | CHEK1 (0.60) | CHEK1 | |
| SCHEMBL12184659 | 0.78 | CHEK1 (0.76) | CHEK1 | |
| SCHEMBL12184821 | 0.77 | CHEK1 (0.75) | CHEK1 | |
| SCHEMBL12184679 | 0.77 | CHEK1 (0.78) | CHEK1 | |
| SCHEMBL12184663 | 0.76 | CHEK1 (0.77) | CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141716-A2 | PHARMACEUTICAL COMPOUNDS | SENTINEL ONCOLOGY LIMITED (GB) | 2011-11-17 | — | — | WO | disclosed |