Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 7/20 | 0.72 |
| ▸ | DRD4 | P21917 | 10/20 | 0.57 |
| ▸ | DRD2 | P14416 | 8/20 | 0.57 |
| ▸ | DRD3 | P35462 | 8/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12185619 | 0.93 | PRCP (0.79) | PRCPDRD4DRD2DRD3CYP1A2 | |
| SCHEMBL14686651 | 0.91 | PRCP (0.76) | PRCPDRD4DRD2DRD3CYP1A2 | |
| SCHEMBL12185591 | 0.88 | PRCP (0.69) | PRCPDRD4DRD2DRD3CYP1A2 | |
| SCHEMBL14686497 | 0.88 | PRCP (0.69) | PRCPDRD4DRD2DRD3CYP1A2 | |
| SCHEMBL14691670 | 0.86 | PRCP (0.69) | PRCPDRD4DRD2DRD3HRH3 | |
| SCHEMBL12185531 | 0.86 | PRCP (0.69) | PRCPDRD4DRD2DRD3CYP1A2 | |
| SCHEMBL12185623 | 0.86 | PRCP (0.69) | PRCPDRD4DRD2DRD3CYP1A2 | |
| SCHEMBL12185553 | 0.85 | PRCP (0.73) | PRCPDRD4DRD2DRD3CYP1A2 | |
| SCHEMBL12185580 | 0.84 | PRCP (1.00) | PRCPDRD4DRD2DRD3CYP1A2 | |
| SCHEMBL14701320 | 0.84 | PRCP (0.66) | PRCPDRD4DRD2DRD3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143057-A1 | NOVEL PROLYLCARBOXYPEPTIDASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2011-11-17 | — | — | WO | disclosed |