Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 12/20 | 0.60 |
| ▸ | PIK3CG | P48736 | 12/20 | 0.60 |
| ▸ | PIK3R1 | P27986 | 7/20 | 0.60 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.48 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.32 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12097 | 0.93 | PIK3CD (0.65) | PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB | |
| SCHEMBL31655798 | 0.88 | PIK3CD (0.78) | PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB | |
| SCHEMBL11274 | 0.88 | PIK3CD (0.78) | PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB | |
| SCHEMBL11985 | 0.87 | PIK3CD (0.77) | PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB | |
| SCHEMBL12233 | 0.86 | PIK3CD (0.63) | PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB | |
| SCHEMBL11872 | 0.85 | PIK3CD (0.65) | PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB | |
| SCHEMBL12007 | 0.84 | PIK3CD (0.64) | PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB | |
| SCHEMBL16001768 | 0.83 | PIK3CD (0.71) | PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB | |
| SCHEMBL8714 | 0.82 | PIK3CD (0.59) | PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB | |
| SCHEMBL14749 | 0.81 | PIK3CD (0.83) | PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2491037-A1 | COMPOUNDS | Respivert Limited (GB) | 2012-08-29 | — | — | EP | disclosed |
| WO-2011048111-A1 | COMPOUNDS | RESPIVERT LIMITED (GB) | 2011-04-28 | — | — | WO | disclosed |