SCHEMBL12196151

SCHEMBL12196151

CCCNC(=O)CC1CN=C(c2cc3cc(Oc4ccc(S(C)(=O)=O)nc4)cc(C)c3[nH]2)S1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCK P35557 12/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL564636 0.91 GCK (0.34) GCK
SCHEMBL564337 0.90 GCK (0.32) GCK
SCHEMBL564625 0.90 GCK (0.33) GCK
SCHEMBL564314 0.90 GCK (0.32) GCK
SCHEMBL564378 0.89 GCK (0.38) GCK
SCHEMBL10240804 0.88 GCK (0.34) GCK
SCHEMBL565089 0.88 GCK (0.34) GCK
SCHEMBL564485 0.87 GCK (0.33) GCK
SCHEMBL1677324 0.85 GCK (0.35) GCK
SCHEMBL10280631 0.85 GCK (0.35) GCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2371826-A1 NOVEL FUSED RING COMPOUND AND USE THEREOF Takeda Pharmaceutical Company Limited (JP) 2011-10-05 EP disclosed