SCHEMBL12199017

SCHEMBL12199017

CCCCc1ccc(-c2cc(F)c(C(F)(F)Oc3cc(F)c(C(F)(F)F)c(F)c3)c(F)c2)c(F)c1

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.37
S1PR1 P21453 5/20 0.35
S1PR3 Q99500 4/20 0.35
PTGS2 P35354 2/20 0.32
FAAH O00519 1/20 0.32
RARA P10276 1/20 0.32
RARG P13631 1/20 0.32
GRM2 Q14416 1/20 0.32
SKP2 Q13309 1/20 0.31
AKR1C3 P42330 1/20 0.30
AKR1C2 P52895 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12205424 0.97 RARB (0.37) RARBS1PR1S1PR3PTGS2FAAH
SCHEMBL14226555 0.97 RARB (0.41) RARBS1PR1S1PR3PTGS2FAAH
SCHEMBL3439572 0.96 RARB (0.35) RARBS1PR1S1PR3PTGS2FAAH
SCHEMBL14884745 0.93 RARB (0.41) RARBS1PR1S1PR3RARARARG
SCHEMBL12226099 0.93 RARB (0.41) RARBS1PR1S1PR3PTGS2FAAH
SCHEMBL16789609 0.93 RARB (0.37) RARBS1PR1S1PR3PTGS2FAAH
SCHEMBL15461665 0.93 PDK2 (0.34) RARBS1PR1S1PR3PTGS2GRM2
SCHEMBL3439579 0.92 RARB (0.39) RARBS1PR1S1PR3PTGS2FAAH
SCHEMBL19751168 0.92 RARB (0.40) RARBS1PR1S1PR3PTGS2FAAH
SCHEMBL14884621 0.92 RARB (0.40) RARBS1PR1S1PR3PTGS2FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360229-B1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL ELEMENT JNC CORP (JP) 2016-08-31 EP disclosed
US-8974694-B2 Liquid-crystal composition JNC CORPORATION (JP) 2015-03-10 US disclosed
US-8974694-B2 Liquid-crystal composition JNC CORPORATION (JP) 2015-03-10 US disclosed
US-20130289316-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE JNC CORP (JP) 2013-10-31 US disclosed
US-20130289316-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE JNC CORP (JP) 2013-10-31 US disclosed
US-8501285-B2 Optically isotropic liquid crystal medium and optical device JNC CORPORATION (JP) 2013-08-06 US disclosed
US-8501285-B2 Optically isotropic liquid crystal medium and optical device JNC CORPORATION (JP) 2013-08-06 US disclosed
US-20130188107-A1 LIQUID-CRYSTAL COMPOSITION JNC PETROCHEMICAL CORPORATION (JP) 2013-07-25 US disclosed
US-20130188107-A1 LIQUID-CRYSTAL COMPOSITION JNC PETROCHEMICAL CORPORATION (JP) 2013-07-25 US disclosed
US-20110242473-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE JNC CORPORATION (JP) 2011-10-06 US disclosed