Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 19/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2477479 | 0.89 | HDAC1 (0.53) | HDAC1HDAC2HDAC3NCOR2HDAC10 | |
| SCHEMBL2471250 | 0.88 | HDAC1 (0.62) | HDAC1HDAC2HDAC3NCOR2HDAC10 | |
| SCHEMBL4392745 | 0.87 | HDAC1 (0.52) | HDAC1HDAC2HDAC3NCOR2HDAC10 | |
| SCHEMBL3832448 | 0.87 | HDAC1 (0.52) | HDAC1HDAC2HDAC3NCOR2HDAC10 | |
| SCHEMBL3835401 | 0.87 | HDAC1 (0.57) | HDAC1HDAC2HDAC3NCOR2HDAC10 | |
| SCHEMBL3835736 | 0.87 | HDAC1 (0.58) | HDAC1HDAC2HDAC3NCOR2HDAC10 | |
| SCHEMBL3835871 | 0.87 | HDAC1 (0.59) | HDAC1HDAC2HDAC3NCOR2HDAC10 | |
| SCHEMBL2479994 | 0.86 | HDAC1 (0.65) | HDAC1HDAC2HDAC3NCOR2HDAC10 | |
| SCHEMBL3835424 | 0.86 | HDAC1 (0.60) | HDAC1HDAC2HDAC3NCOR2HDAC10 | |
| SCHEMBL2474631 | 0.85 | HDAC1 (0.50) | HDAC1HDAC2HDAC3NCOR2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2107052-B1 | NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE | SANTEN PHARMACEUTICAL CO LTD (JP) | 2011-10-12 | — | — | EP | disclosed |