SCHEMBL12200083

SCHEMBL12200083

O=C1C=CC2C=CC=CC2O1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12825236 0.72
SCHEMBL19397277 0.72
SCHEMBL10238806 0.69 XPO1 (0.30)
SCHEMBL5778865 0.65
SCHEMBL26192195 0.62
SCHEMBL26263043 0.61 DHODH (0.34)
SCHEMBL8235591 0.61
SCHEMBL20982186 0.60
SCHEMBL14532637 0.60
SCHEMBL10990251 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170044171-A1 COMPOUNDS FOR PREPARING PYRROLE SIX-MEMBERED HETEROARYL RING DERIVATIVE JIANGSU HENGRUI MEDICINE CO (CN) 2017-02-16 US disclosed
US-20170044171-A1 COMPOUNDS FOR PREPARING PYRROLE SIX-MEMBERED HETEROARYL RING DERIVATIVE JIANGSU HENGRUI MEDICINE CO (CN) 2017-02-16 US disclosed
US-8580786-B2 Triazine derivatives and their therapeutical applications NANT HOLDINGS IP, LLC (US) 2013-11-12 US disclosed
US-8580786-B2 Triazine derivatives and their therapeutical applications NANT HOLDINGS IP, LLC (US) 2013-11-12 US disclosed
EP-1624035-B1 PRINTING INK CONTAINING FLUORESCENT COLORANTS AND INK-JET RECORDING METHOD CANON KK (JP) 2013-01-09 EP disclosed
US-8308198-B2 Water-based fluorescent ink, recorded image using the same, and judging method CANON KABUSHIKI KAISHA (JP) 2012-11-13 US disclosed
US-8308198-B2 Water-based fluorescent ink, recorded image using the same, and judging method CANON KABUSHIKI KAISHA (JP) 2012-11-13 US disclosed
US-20120238576-A1 Triazine Derivatives and their Therapeutical Applications CALIFORNIA CAPITAL EQUITY, LLC (CA) 2012-09-20 US disclosed
US-20110245226-A1 PIPERIDINYL DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY BRISTOL-MYERS SQUIBB COMPANY 2011-10-06 US disclosed
US-20110150763-A1 TRIAZINE DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS ABRAXIS BIOSCIENCE, LLC (US) 2011-06-23 US disclosed
US-20080176853-A1 e.g. N-(2-chloro-6-methylphenyl)-3-ethoxyacrylamide; protein (tyrosine and serine/threonine) kinase inhibitor; variety of conditions and diseases; antiproliferative, anticarcinogenic, antiinflammatory, antiallergenic agent; autoimmune and neurodegenerative disorders ABRAXIS BIOSCIENCE, INC. (US) 2008-07-24 US disclosed
US-20080176853-A1 e.g. N-(2-chloro-6-methylphenyl)-3-ethoxyacrylamide; protein (tyrosine and serine/threonine) kinase inhibitor; variety of conditions and diseases; antiproliferative, anticarcinogenic, antiinflammatory, antiallergenic agent; autoimmune and neurodegenerative disorders ABRAXIS BIOSCIENCE, INC. (US) 2008-07-24 US disclosed
US-7388027-B2 Bicyclic compounds as modulators of androgen receptor function and method BRISTOL-MYERS SQUIBB COMPANY (US) 2008-06-17 US disclosed
US-7388027-B2 Bicyclic compounds as modulators of androgen receptor function and method BRISTOL-MYERS SQUIBB COMPANY (US) 2008-06-17 US disclosed
US-20070185097-A1 MELANIN CONCENTRATING HORMONE RECEPTOR-1 ANTAGONISTS BRISTOL-MYERS SQUIBB COMPANY 2007-08-09 US disclosed
US-20070185097-A1 MELANIN CONCENTRATING HORMONE RECEPTOR-1 ANTAGONISTS BRISTOL-MYERS SQUIBB COMPANY 2007-08-09 US disclosed
US-20070034114-A1 Can improve both fluorescence properties and water resistance of the image, which has been difficult with conventional fluorescent coloring materials, and can contain a large amount of a fluorescent coloring material, and in addition, improved sticking resistance and reliability CANON KABUSHIKI KAISHA (JP) 2007-02-15 US disclosed
US-20070034114-A1 Can improve both fluorescence properties and water resistance of the image, which has been difficult with conventional fluorescent coloring materials, and can contain a large amount of a fluorescent coloring material, and in addition, improved sticking resistance and reliability CANON KABUSHIKI KAISHA (JP) 2007-02-15 US disclosed
US-20070029522-A1 Print ink containing a plurality of fluorescent coloring materials and inkjet recording method CANON KABUSHIKI KAISHA (JP) 2007-02-08 US disclosed
US-20070029522-A1 Print ink containing a plurality of fluorescent coloring materials and inkjet recording method CANON KABUSHIKI KAISHA (JP) 2007-02-08 US disclosed