Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 19/20 | 0.56 |
| ▸ | MAOA | P21397 | 19/20 | 0.56 |
| ▸ | MAOB | P27338 | 19/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15766920 | 0.72 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL15767093 | 0.72 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL20547538 | 0.72 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL15766921 | 0.72 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL15767095 | 0.72 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL15767314 | 0.72 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL10299905 | 0.71 | S1PR3 (0.54) | — | |
| Hydrochloric Acid SCHEMBL15767128 | 0.71 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL15777419 | 0.71 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL15767129 | 0.71 | KDM1A (1.00) | KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329676-B2 | Cycloalkane-containing sphingosine 1-phosphate agonists | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2012-12-11 | — | — | US | disclosed |
| US-20110245204-A1 | CYCLOALKANE-CONTAINING SPHINGOSINE 1-PHOSPHATE AGONISTS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2011-10-06 | — | — | US | disclosed |
| US-8008286-B2 | Method for treatment of neuropathic pain | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2011-08-30 | — | — | US | disclosed |
| US-7754703-B2 | Cycloalkane-containing sphingosine 1-phosphate agonists | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2010-07-13 | — | — | US | disclosed |
| US-20090062238-A1 | METHOD FOR TREATMENT OF NEUROPATHIC PAIN | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2009-03-05 | — | — | US | disclosed |
| US-20080249070-A1 | Cycloalkane-Containing Sphingosine 1-Phospate Agonists | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245204-A1 | CYCLOALKANE-CONTAINING SPHINGOSINE 1-PHOSPHATE AGONISTS | S1PR1, S1PR3, S1PR4 | KDM1A 3861/4885MAOA 4442/4885MAOB 4321/4885 |
| US-20090062238-A1 | METHOD FOR TREATMENT OF NEUROPATHIC PAIN | S1PR2, S1PR1, S1PR4 | KDM1A 3357/4885MAOA 2859/4885MAOB 2423/4885 |
| US-20080249070-A1 | Cycloalkane-Containing Sphingosine 1-Phospate Agonists | S1PR1, S1PR3, S1PR4 | KDM1A 3566/4885MAOA 4407/4885MAOB 4356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.