SCHEMBL12200614

SCHEMBL12200614

Cc1cc(CN(c2nnn(C)n2)[C@H]2CCCN(CC3CCN(C)CC3)c3c2cc(C)c(C(F)(F)F)c3C)cc(C(F)(F)F)c1

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2474994 0.96 CETP (0.67) CETP
SCHEMBL2474996 0.96 CETP (0.67) CETP
SCHEMBL2479545 0.93 CETP (0.72) CETP
SCHEMBL2479547 0.93 CETP (0.72) CETP
Hydrochloric Acid SCHEMBL2477764 0.92 CETP (0.71) CETP
SCHEMBL2480161 0.92 CETP (0.69) CETP
SCHEMBL2480159 0.92 CETP (0.69) CETP
Hydrochloric Acid SCHEMBL2477766 0.92 CETP (0.71) CETP
SCHEMBL2479209 0.89 CETP (0.66) CETP
SCHEMBL2472499 0.89 CETP (0.66) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1761522-B1 COMPOUNDS AND METHODS FOR TREATING DYSLIPIDEMIA LILLY CO ELI (US) 2011-10-12 EP disclosed