SCHEMBL12201351

SCHEMBL12201351

Cc1cc(C)cc(CN(c2nnn(C)n2)[C@H]2CCCN(C(=O)OC3CCCC3)c3cc4c(cc32)CCC4)c1

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2477522 0.90 CETP (0.53) CETP
SCHEMBL2477518 0.90 CETP (0.53) CETP
SCHEMBL2479009 0.80 CETP (0.53) CETP
SCHEMBL2479007 0.80 CETP (0.53) CETP
SCHEMBL1380464 0.80 CETP (0.52) CETP
SCHEMBL1380462 0.80 CETP (0.52) CETP
SCHEMBL12200635 0.80 CETP (0.53) CETP
SCHEMBL1381844 0.79 CETP (0.62) CETP
SCHEMBL2481317 0.79 CETP (0.62) CETP
SCHEMBL1381841 0.79 CETP (0.62) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1761522-B1 COMPOUNDS AND METHODS FOR TREATING DYSLIPIDEMIA LILLY CO ELI (US) 2011-10-12 EP disclosed