Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 16/20 | 0.70 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | USP19 | O94966 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12201409 | 0.91 | GCK (0.68) | GCKCNR2 | |
| SCHEMBL12201388 | 0.88 | GCK (0.70) | GCK | |
| SCHEMBL12201490 | 0.88 | GCK (0.70) | GCK | |
| SCHEMBL2515235 | 0.83 | GCK (0.75) | GCK | |
| SCHEMBL2513851 | 0.83 | GCK (0.70) | GCK | |
| SCHEMBL2512504 | 0.82 | GCK (0.68) | GCK | |
| SCHEMBL2510380 | 0.82 | GCK (0.82) | GCK | |
| SCHEMBL12201202 | 0.81 | GCK (0.66) | GCKUSP19 | |
| SCHEMBL12201392 | 0.81 | GCK (0.67) | GCK | |
| SCHEMBL12201492 | 0.81 | GCK (0.68) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034822-B2 | Glucokinase activators | TAKEDA SAN DIEGO, INC. (US) | 2011-10-11 | — | — | US | disclosed |
| US-20070213349-A1 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213349-A1 | GLUCOKINASE ACTIVATORS | GCK, GCKR, GALK1 | GCK 1/4885CNR2 4737/4885USP19 2383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.