Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL88602 | 0.88 | TUBB1 (0.47) | TUBB1 | |
| SCHEMBL90776 | 0.87 | TUBB1 (0.44) | TUBB1 | |
| SCHEMBL14233111 | 0.87 | TUBB1 (0.40) | TUBB1 | |
| SCHEMBL14210660 | 0.87 | TUBB1 (0.40) | TUBB1 | |
| SCHEMBL12203106 | 0.87 | TUBB1 (0.44) | TUBB1 | |
| SCHEMBL58210 | 0.85 | TUBB1 (0.43) | TUBB1 | |
| SCHEMBL14567895 | 0.84 | TUBB1 (0.43) | TUBB1 | |
| SCHEMBL22692394 | 0.84 | TUBB1 (0.42) | TUBB1 | |
| SCHEMBL22692400 | 0.84 | TUBB1 (0.38) | TUBB1 | |
| SCHEMBL58031 | 0.83 | TUBB1 (0.42) | TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374454-A1 | Hemiasterlin derivatives and uses thereof in the treatment of cancer | Eisai R&D Management Co., Ltd. (JP) | 2011-10-12 | — | — | EP | disclosed |