Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 4/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1827758 | 1.00 | CA1 (0.61) | CA1CA2ACE2EPHX1TP53 | |
| SCHEMBL1827755 | 1.00 | CA1 (0.61) | CA1CA2ACE2EPHX1TP53 | |
| SCHEMBL10866301 | 0.98 | CA1 (0.59) | CA1CA2ACE2EPHX1TP53 | |
| SCHEMBL12326336 | 0.98 | CA1 (0.59) | CA1CA2ACE2EPHX1TP53 | |
| SCHEMBL7712209 | 0.98 | CA1 (0.59) | CA1CA2ACE2EPHX1TP53 | |
| SCHEMBL23857835 | 0.98 | CA1 (0.59) | CA1CA2ACE2EPHX1TP53 | |
| SCHEMBL5423239 | 0.98 | CA1 (0.59) | CA1CA2ACE2EPHX1TP53 | |
| SCHEMBL277898 | 0.98 | CA1 (0.59) | CA1CA2ACE2EPHX1TP53 | |
| SCHEMBL2348891 | 0.98 | CA1 (0.59) | CA1CA2ACE2EPHX1TP53 | |
| SCHEMBL13854594 | 0.98 | CA1 (0.59) | CA1CA2ACE2EPHX1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100410-B1 | MUSCARINIC RECEPTOR 4 ANTAGONISTS AND METHODS OF USE | NEUROCRINE BIOSCIENCES INC (US) | 2026-04-22 | — | — | EP | claimed |
| CN-113015735-B | 5-Hydroxy-7-oxabicyclo [2.2.1] heptane-2-carboxamide derivatives for inducing chondrogenesis for the treatment of joint damage | 诺华股份有限公司 | 2024-06-21 | — | — | CN | claimed |
| CN-118103374-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-118076354-A | Methods of treating migraine with MNK inhibitors | 4E治疗公司 | 2024-05-24 | — | — | CN | claimed |
| CN-118019742-A | Novel benzodiazepine derivatives as GABA Aγ1 PAM | 豪夫迈·罗氏有限公司 | 2024-05-10 | — | — | CN | claimed |
| EP-4363419-A1 | SPIROCYCLIC PYRIDINE-1,5-DIONES EXHIBITING MNK INHIBITION AND THEIR METHOD OF USE | 4E Therapeutics, Inc. (US) | 2024-05-08 | — | — | EP | claimed |
| CN-117980305-A | Spirocyclic pyridine-1, 5-diones exhibiting MNK inhibition and methods of use thereof | 4E治疗公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117881393-A | Aqueous gel composition | 阿库西亚医疗有限责任公司 | 2024-04-12 | — | — | CN | claimed |
| CN-112292380-B | N- (phenyl) -2- (phenyl) pyrimidine-4-carboxamide derivatives and related compounds as HPK1 inhibitors for the treatment of cancer | 因赛特公司 | 2024-04-05 | — | — | CN | claimed |
| CN-117794896-A | Protease inhibitors for the treatment of coronavirus infections | 斯克里普斯研究学院 | 2024-03-29 | — | — | CN | claimed |
| EP-1255726-A2 | (R)-2-ARYL-PROPIONAMIDES, USEFUL IN THE INHIBITION OF IL-8 INDUCED CHEMIOTAXIS OF NEUTROPHILS | Dompé S.P.A. (IT) | 2002-11-13 | — | — | EP | claimed |
| WO-2002068377-A1 | OMEGA-AMINOALKYLAMIDES OF R-2-ARYL-PROPIONIC ACIDS AS INHIBITORS OF THE CHEMOTAXIS OF POLYMORPHONUCLEATE AND MONONUCLEATE CELLS | Dompé S.p.A. (IT) | 2002-09-06 | — | — | WO | claimed |
| EP-1147078-A1 | ACETYLENIC (BETA)-SULFONAMIDO AND PHOSPHINIC ACID AMIDE HYDROXAMIC ACID TACE INHIBITORS | American Cyanamid Company (US) | 2001-10-24 | — | — | EP | claimed |
| WO-2001058852-A2 | (R)-2-ARYL-PROPIONAMIDES, USEFUL IN THE INHIBITION OF IL-8-INDUCED CHEMIOTAXIS OF NEUTROPHILS | Dompé S.p.A. (IT) | 2001-08-16 | — | — | WO | claimed |
| WO-2000044711-A1 | ACETYLENIC $G(b)-SULFONAMIDO AND PHOSPHINIC ACID AMIDE HYDROXAMIC ACID TACE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 2000-08-03 | — | — | WO | claimed |
| US-5766918-A | SYNTHESIS OF PROPIONIC ACIDS FROM RACEMIC AMIDES | RHONE-POULENC SANTE (FR) | 1998-06-16 | — | — | US | claimed |
| EP-0433117-B1 | Novel polypeptides, the DNA sequences allowing their expression, method of preparation, and utilization | RHONE POULENC SANTE (FR) | 1997-05-02 | — | — | EP | claimed |
| EP-0330529-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 2-ARYL-PROPIONIC ACIDS | RHONE-POULENC SANTE (FR) | 1993-03-31 | — | — | EP | claimed |
| US-5089405-A | Hydrolysis of racemic 2-arylpropionamides | RHONE-POULENC SANTE (FR) | 1992-02-18 | — | — | US | claimed |
| EP-0433117-A1 | Novel polypeptides, the DNA sequences allowing their expression, method of preparation, and utilization | RHONE-POULENC SANTE (FR) | 1991-06-19 | — | — | EP | claimed |