Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 0.37 |
| ▸ | EHMT1 | Q9H9B1 | 9/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 8/20 | 0.35 |
| ▸ | GPR6 | P46095 | 2/20 | 0.35 |
| ▸ | TNF | P01375 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12921314 | 0.92 | PDE4D (0.36) | PDE4DEHMT1EHMT2GPR6TNF | |
| SCHEMBL186760 | 0.92 | GPR6 (0.38) | PDE4DEHMT1EHMT2GPR6TNF | |
| SCHEMBL8055440 | 0.92 | PDE4D (0.45) | PDE4DEHMT1EHMT2GPR6 | |
| SCHEMBL12921369 | 0.92 | PDE4D (0.37) | PDE4DEHMT1EHMT2DNMT3A | |
| SCHEMBL12209084 | 0.91 | ACACB (0.38) | EHMT1EHMT2 | |
| SCHEMBL187336 | 0.91 | GPR6 (0.38) | PDE4DEHMT1EHMT2GPR6TNF | |
| SCHEMBL12921822 | 0.90 | GPR6 (0.46) | PDE4DGPR6 | |
| SCHEMBL12921323 | 0.90 | PDE4D (0.36) | PDE4DEHMT1EHMT2GPR6TNF | |
| SCHEMBL557917 | 0.89 | EGLN1 (0.40) | PDE4DGPR6TNF | |
| SCHEMBL10266742 | 0.89 | EGLN1 (0.40) | PDE4DGPR6TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2380891-A1 | Substituted piperidino-dihydrothienopyrimidines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-10-26 | — | — | EP | disclosed |