SCHEMBL12213232

SCHEMBL12213232

CCC1(CC)c2cc(-c3cc4c(cc3-c3ccc5c(c3)C(CC)(CC)c3cc([Si](C)(C)C)ccc3-5)C(CC)(CC)c3cc(-c5ccc6c(c5)C(CC)(CC)c5cc([Si](C)(C)C)ccc5-6)c(-c5ccc6c(c5)C(CC)(CC)c5cc([Si](C)(C)C)ccc5-6)cc3-4)ccc2-c2ccc([Si](C)(C)C)cc21

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ PGR P06401 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16358511 0.77 PDK2 (0.33) —
SCHEMBL16358513 0.74 PDK2 (0.44) —
SCHEMBL12213220 0.73 PDK2 (0.45) —
SCHEMBL16358899 0.72 PDK2 (0.34) —
SCHEMBL12213214 0.72 PDK2 (0.44) —
SCHEMBL16358514 0.72 PDK2 (0.41) PGR
SCHEMBL12213258 0.72 PDK2 (0.43) —
SCHEMBL16358498 0.72 PDK2 (0.38) PGR
SCHEMBL12213253 0.71 PDK2 (0.48) —
SCHEMBL19704580 0.70 PDK2 (0.38) PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8039128-B2 Fluorene compound, organic light emitting device and display device using the fluorene compound CANON KABUSHIKI KAISHA (JP) 2011-10-18 — — US disclosed
US-20100072885-A1 FLUORENE COMPOUND, ORGANIC LIGHT EMITTING DEVICE AND DISPLAY DEVICE USING THE FLUORENE COMPOUND CANON KABUSHIKI KAISHA (JP) 2010-03-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100072885-A1 FLUORENE COMPOUND, ORGANIC LIGHT EMITTING DEVICE AND DISPLAY DEVICE USING THE FLUORENE COMPOUND ARL1, AFF1, AFF2 PGR 1962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback