Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 3/20 | 0.37 |
| ▸ | PRKCG | P05129 | 3/20 | 0.37 |
| ▸ | PRKCB | P05771 | 3/20 | 0.37 |
| ▸ | PRKCA | P17252 | 3/20 | 0.37 |
| ▸ | PRKCH | P24723 | 3/20 | 0.37 |
| ▸ | PRKCI | P41743 | 3/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.37 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.37 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28228592 | 0.83 | HSD17B10 (0.39) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL23171105 | 0.81 | LPAR1 (0.42) | LPAR6LPAR1LPAR4LPAR5LPAR2 | |
| SCHEMBL28615403 | 0.80 | PRKD3 (0.34) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL872791 | 0.78 | PRKD3 (0.33) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL15800638 | 0.77 | LPAR6 (0.36) | LPAR6LPAR1LPAR4LPAR5LPAR2 | |
| SCHEMBL12418703 | 0.75 | LPAR1 (0.42) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL17213403 | 0.75 | CNR1 (0.40) | PRKCAPRKCEPRKCQPRKCDLPAR6 | |
| SCHEMBL17666792 | 0.74 | PRKD3 (0.53) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL252989 | 0.72 | PRKD3 (0.51) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL8674072 | 0.72 | PRKD3 (0.56) | PRKD3PRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10653780-B2 | Amino lipids and methods for the delivery of nucleic acids | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2020-05-19 | — | — | US | disclosed |
| EP-3225621-A1 | IMPROVED AMINO LIPIDS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS | Arbutus Biopharma Corporation (CA) | 2017-10-04 | — | — | EP | disclosed |
| EP-2743265-B1 | Improved amino lipids and methods for the delivery of nucleic acids | ARBUTUS BIOPHARMA CORP (CA) | 2017-03-15 | — | — | EP | disclosed |
| US-20160095924-A1 | AMINO LIPIDS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2016-04-07 | — | — | US | disclosed |
| US-20160095924-A1 | AMINO LIPIDS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2016-04-07 | — | — | US | disclosed |
| US-9139554-B2 | Amino lipids and methods for the delivery of nucleic acids | TEKMIRA PHARMACEUTICALS CORPORATION (CA) | 2015-09-22 | — | — | US | disclosed |
| US-9139554-B2 | Amino lipids and methods for the delivery of nucleic acids | TEKMIRA PHARMACEUTICALS CORPORATION (CA) | 2015-09-22 | — | — | US | disclosed |
| EP-2350043-B9 | IMPROVED AMINO LIPIDS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS | TEKMIRA PHARMACEUTICALS CORP (CA) | 2014-08-20 | — | — | EP | disclosed |
| EP-2350043-B1 | IMPROVED AMINO LIPIDS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS | TEKMIRA PHARMACEUTICALS CORP (CA) | 2014-03-26 | — | — | EP | disclosed |
| US-20110256175-A1 | AMINO LIPIDS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2011-10-20 | — | — | US | disclosed |
| US-20110256175-A1 | AMINO LIPIDS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2011-10-20 | — | — | US | disclosed |
| WO-2010042877-A1 | IMPROVED AMINO LIPIDS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS | TEKMIRA PHARMACEUTICALS CORPORATION (CA) | 2010-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160095924-A1 | AMINO LIPIDS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS | NSUN3, SARNP, LDLR | PRKD3 3813/4885PRKCG 2328/4885PRKCB 2818/4885 |
| US-10653780-B2 | Amino lipids and methods for the delivery of nucleic acids | NSUN3, SARNP, LDLR | PRKD3 3813/4885PRKCG 2328/4885PRKCB 2818/4885 |
| US-20110256175-A1 | AMINO LIPIDS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS | NSUN3, SARNP, LDLR | PRKD3 3813/4885PRKCG 2328/4885PRKCB 2818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.