SCHEMBL12217153

SCHEMBL12217153

CN1/C(=C/C=C2\C(=O)c3ccccc3C2=C(C#N)C#N)C(C)(C)c2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 15/20 0.61
MEN1 O00255 14/20 0.61
KMT2A Q03164 14/20 0.61
HTT P42858 7/20 0.61
USP2 O75604 6/20 0.61
POLB P06746 5/20 0.61
RAB9A P51151 4/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
NPC1 O15118 2/20 0.61
CRHBP P24387 3/20 0.57
CRHR2 Q13324 3/20 0.57
KEAP1 Q14145 1/20 0.57
NFE2L2 Q16236 1/20 0.57
LMNA P02545 7/20 0.54
CYP3A4 P08684 2/20 0.54
CYP2C19 P33261 2/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2C9 P11712 1/20 0.54
ALDH1A1 P00352 5/20 0.48
MAPK1 P28482 5/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9637127 0.87 MAPT (0.77) MAPTMEN1KMT2AHTTUSP2
SCHEMBL9637124 0.87 MAPT (0.77) MAPTMEN1KMT2AHTTUSP2
SCHEMBL12217150 0.85 MAPT (0.45) MAPTMEN1KMT2AHTTUSP2
SCHEMBL12217152 0.83 MAPT (0.43) MAPTMEN1KMT2AHTTUSP2
SCHEMBL25849800 0.83 KMT2A (0.42) MAPTMEN1KMT2AHTTUSP2
SCHEMBL13222294 0.81 MAPT (0.71) MAPTMEN1KMT2AHTTUSP2
SCHEMBL25850879 0.80 MEN1 (0.45) MAPTMEN1KMT2AHTTUSP2
SCHEMBL25165243 0.79 KMT2A (0.40) MAPTMEN1KMT2AHTTUSP2
SCHEMBL25850036 0.78 MAPT (0.64) MAPTMEN1KMT2AHTTUSP2
SCHEMBL23515503 0.78 MAPT (0.54) MAPTMEN1KMT2AHTTUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed
US-11152581-B2 Visibly transparent, near-infrared-absorbing donor/acceptor photovoltaic devices UBIQUITOUS ENERGY, INC. (US) 2021-10-19 US disclosed
US-20210184145-A1 VISIBLY TRANSPARENT PHOTOACTIVE COMPOUNDS FOR NEAR-INFRARED-ABSORBING PHOTOVOLTAIC DEVICES UBIQUITOUS ENERGY, INC. (US) 2021-06-17 US disclosed
US-20110256422-A1 MEROCYANINES FOR PRODUCING PHOTOACTIVE LAYERS FOR ORGANIC SOLAR CELLS AND ORGANIC PHOTODETECTORS BASF SE (DE) 2011-10-20 US disclosed
US-20110256422-A1 MEROCYANINES FOR PRODUCING PHOTOACTIVE LAYERS FOR ORGANIC SOLAR CELLS AND ORGANIC PHOTODETECTORS BASF SE (DE) 2011-10-20 US disclosed
WO-2010049512-A1 MEROCYANINES FOR PRODUCING PHOTOACTIVE LAYERS FOR ORGANIC SOLAR CELLS AND ORGANIC PHOTODETECTORS BASF SE (DE) 2010-05-06 WO disclosed