⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22168562 | 0.78 | — | — | |
| SCHEMBL18001656 | 0.75 | — | — | |
| SCHEMBL16029290 | 0.75 | — | — | |
| SCHEMBL17704675 | 0.75 | — | — | |
| SCHEMBL18715916 | 0.75 | — | — | |
| SCHEMBL11628755 | 0.71 | — | — | |
| SCHEMBL19054427 | 0.71 | — | — | |
| SCHEMBL25475674 | 0.71 | — | — | |
| SCHEMBL17793364 | 0.71 | — | — | |
| SCHEMBL8006453 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382920-A1 | SHMT Inhibitors | THE TRUSTEES OF PRINCETON UNIVERSITY | 2023-11-30 | — | — | US | disclosed |
| WO-2020041301-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT FACTOR D MEDICAL DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |
| US-20110257146-A1 | Method of Treating Kcnq Related Disorders Using Organozinc Compounds | THE JOHNS HOPKINS UNIVERSITY (US) | 2011-10-20 | — | — | US | disclosed |
| US-8007926-B2 | Luminescent compounds with carbene ligands | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2011-08-30 | — | — | US | disclosed |
| US-20090140640-A1 | LUMINESCENT COMPOUNDS WITH CARBENE LIGANDS | THOMPSON MARK E | 2009-06-04 | — | — | US | disclosed |
| US-7393599-B2 | Luminescent compounds with carbene ligands | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2008-07-01 | — | — | US | disclosed |