⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9594618 | 0.78 | — | — | |
| SCHEMBL12988444 | 0.78 | — | — | |
| SCHEMBL1471438 | 0.78 | — | — | |
| SCHEMBL3919686 | 0.78 | — | — | |
| SCHEMBL3921740 | 0.78 | — | — | |
| SCHEMBL3923402 | 0.78 | — | — | |
| SCHEMBL10325185 | 0.67 | — | — | |
| SCHEMBL16416488 | 0.65 | — | — | |
| SCHEMBL16731349 | 0.63 | — | — | |
| SCHEMBL13497146 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 497 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112800-A1 | METHODS FOR DEPROTECTING AND PURIFYING OLIGONUCLEOTIDE COMPOUNDS | IONIS PHARMACEUTICALS, INC. (US) | 2024-05-30 | — | — | WO | claimed |
| EP-4136092-A1 | COMPOUNDS AND METHODS FOR MODULATING ANGIOTENSINOGEN EXPRESSION | Ionis Pharmaceuticals, Inc. (US) | 2023-02-22 | — | — | EP | claimed |
| CN-115701998-A | Compounds and methods for reducing KCNT1 expression | IONIS制药公司 | 2023-02-14 | — | — | CN | claimed |
| WO-2022109139-A1 | COMPOUNDS AND METHODS FOR MODULATING ANGIOTENSINOGEN EXPRESSION | IONIS PHARMACEUTICALS, INC. (US) | 2022-05-27 | — | — | WO | claimed |
| CN-113286886-A | Compounds and methods for reducing prion expression | IONIS制药公司 | 2021-08-20 | — | — | CN | claimed |
| CN-107602649-B | Glycan molecule is coupled diketopyrrolo-pyrrole compound and preparation method thereof | 龙口联合化学有限公司 | 2019-10-18 | — | — | CN | claimed |
| CN-109688817-A | The fluorescence detection and its analysis method of amine and hydrazine | ILLUMINA公司 | 2019-04-26 | — | — | CN | claimed |
| CN-108136040-A | For the multiple ligand reagent of drug delivery | 阿克丘勒斯治疗公司 | 2018-06-08 | — | — | CN | claimed |
| CN-107602649-A | Glycan molecule coupling diketopyrrolo-pyrrole compound and preparation method thereof | 龙口联合化学有限公司 | 2018-01-19 | — | — | CN | claimed |
| CN-104262437-B | The synthetic method of nonnatural base monomer heterocycle and pyrithione deoxyribonucleoside triphosphate and its derivative | 河南师范大学 | 2017-08-15 | — | — | CN | claimed |
| WO-2004072238-A2 | TERMINAL-PHOSPHATE-LABELED NUCLEOTIDES WITH NEW LINKERS | AMERSHAM BIOSCIENCES CORP (US) | 2004-08-26 | — | — | WO | claimed |
| WO-2003072066-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF GLAUCOMA AND OCULAR HYPERTENSION | INSPIRE PHARMACEUTICALS, INC. (US) | 2003-09-04 | — | — | WO | claimed |
| CN-1292381-A | Synthesis of arabinonucleic acid and poly I:C | ZHANG QIJIU (CN) | 2001-04-25 | — | — | CN | claimed |
| CN-1260801-A | Novel glycosylated ginkgolide derivatives, their applicated as medicines and pharmaceutical compositions | CONSEILS DE RES S ET D APPLIC (FR) | 2000-07-19 | — | — | CN | claimed |
| CN-1042429-C | Pyrimidinedione derivative used as antitumor drug, pharmaceutical composition and preparation method | MERRELL PHARMA INC (US) | 1999-03-10 | — | — | CN | claimed |
| CN-1130909-A | 5-(1-fluoro-vinyl)-1H-pyrimidine-2,4-dione derivatives useful as antineoplastic agents | MERRELL DOW PHARMA (US) | 1996-09-11 | — | — | CN | claimed |
| EP-0464112-A1 | A PROCESS FOR THE PREPARATION OF 9-SUBSTITUTED GUANINE DERIVATIVES AND INTERMEDIATES FOR USE IN THE PROCESS. | GEA FARMACEUTISK FABRIK AS (DK) | 1992-01-08 | — | — | EP | claimed |
| EP-0038569-B1 | DEAZAPURINE NUCLEOSIDES, FORMULATIONS AND PREPARATION THEREOF | THE WELLCOME FOUNDATION LIMITED (GB) | 1985-01-30 | — | — | EP | claimed |
| US-4381344-A | Process for producing deoxyribosides using bacterial phosphorylase | BURROUGHS WELLCOME CO. (US) | 1983-04-26 | — | — | US | claimed |
| EP-0038569-A2 | Deazapurine nucleosides, formulations and preparation thereof | THE WELLCOME FOUNDATION LIMITED (GB) | 1981-10-28 | — | — | EP | claimed |