Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 20/20 | 0.82 |
| ▸ | F3 | P13726 | 20/20 | 0.82 |
| ▸ | PLG | P00747 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12220229 | 0.95 | F7 (0.80) | F7F3PLG | |
| SCHEMBL12241604 | 0.90 | F7 (0.87) | F7F3PLG | |
| SCHEMBL2527336 | 0.90 | F7 (1.00) | F7F3PLG | |
| SCHEMBL3834872 | 0.90 | F7 (1.00) | F7F3PLG | |
| SCHEMBL12220224 | 0.86 | F7 (0.66) | F7F3PLG | |
| SCHEMBL12243341 | 0.84 | F7 (0.87) | F7F3PLG | |
| SCHEMBL12220233 | 0.84 | F7 (0.80) | F7F3PLG | |
| SCHEMBL2528430 | 0.84 | F7 (1.00) | F7F3PLG | |
| SCHEMBL8189376 | 0.81 | F7 (0.88) | F7F3 | |
| SCHEMBL2528779 | 0.80 | F7 (1.00) | F7F3PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039506-B2 | Bicyclic lactam factor VIIa inhibitors useful as anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-10-18 | — | — | US | disclosed |