SCHEMBL12220643

SCHEMBL12220643

CC1(C)CCC=C1c1cc(COc2cccc(C(CC(=O)O)C3CC3)c2)ccc1-c1cc(C(F)(F)F)ccc1F

nearest known ligand 0.82

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2499362 1.00 FFAR1 (0.82) FFAR1
SCHEMBL2502272 1.00 FFAR1 (0.82) FFAR1
SCHEMBL2506445 0.93 FFAR1 (0.73) FFAR1
SCHEMBL12220647 0.93 FFAR1 (0.73) FFAR1
SCHEMBL2498610 0.93 FFAR1 (0.73) FFAR1
SCHEMBL2494896 0.91 FFAR1 (0.86) FFAR1
SCHEMBL2503645 0.91 FFAR1 (0.86) FFAR1
SCHEMBL2502038 0.90 FFAR1 (1.00) FFAR1
SCHEMBL2503864 0.90 FFAR1 (0.84) FFAR1
SCHEMBL3705727 0.90 FFAR1 (1.00) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009048527-A1 SUBSTITUTED BIPHENYL GPR40 MODULATORS AMGEN INC. (US) 2009-04-16 WO disclosed