⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264454 | 1.00 | — | — | |
| SCHEMBL14230823 | 1.00 | — | — | |
| SCHEMBL6142704 | 1.00 | — | — | |
| SCHEMBL10201228 | 1.00 | — | — | |
| SCHEMBL14198626 | 1.00 | — | — | |
| SCHEMBL12928828 | 1.00 | — | — | |
| SCHEMBL12899682 | 1.00 | — | — | |
| SCHEMBL12899649 | 1.00 | — | — | |
| SCHEMBL5021289 | 1.00 | — | — | |
| SCHEMBL12149455 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120264707-A1 | BETA-L-2'-DEOXY-NUCLEOSIDES FOR THE TREATMENT OF HEPATITIS B | IDENIX PHARMACEUTICALS, INC. (US) | 2012-10-18 | — | — | US | disclosed |
| US-20110257120-A1 | BETA-L-2'-DEOXY-NUCLEOSIDES FOR THE TREATMENT OF HEPATITIS B | IDENIX PHARMACEUTICALS, INC. (US) | 2011-10-20 | — | — | US | disclosed |
| EP-1296995-B1 | 3'-PRODRUGS OF 2'-DEOXY-BETA-L-NUCLEOSIDES | IDENIX CAYMAN LTD (KY) | 2008-10-15 | — | — | EP | disclosed |
| US-20080064655-A1 | Beta-L-2'-Deoxy-Nucleosides for the Treatment of Hepatitis B | INDENIX PHARMACEUTICALS, INC. (US) | 2008-03-13 | — | — | US | disclosed |