SCHEMBL12223230

SCHEMBL12223230

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nearest known ligand 0.73

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ SIGLEC7 Q9Y286 6/20 0.73
▸ MAG P20916 6/20 0.59
▸ SELL P14151 1/20 0.55
▸ SELP P16109 1/20 0.55
▸ LGALS8 O00214 1/20 0.49
▸ LGALS3 P17931 1/20 0.49
▸ LGALS4 P56470 1/20 0.49
▸ SELE P16581 3/20 0.49
▸ CD22 P20273 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12223144 1.00 SIGLEC7 (0.73) SIGLEC7MAGSELLSELPLGALS8
SCHEMBL15706045 1.00 SIGLEC7 (0.73) SIGLEC7MAGSELLSELPLGALS8
SCHEMBL24368714 0.97 SIGLEC7 (0.74) SIGLEC7MAGSELLSELPSELE
SCHEMBL17988587 0.92 SIGLEC7 (0.71) SIGLEC7MAGSELLSELPLGALS8
SCHEMBL19248964 0.91 SIGLEC7 (0.74) SIGLEC7MAGSELLSELPSELE
SCHEMBL17889798 0.90 SIGLEC7 (0.74) SIGLEC7MAGSELLSELPSELE
SCHEMBL17889802 0.90 SIGLEC7 (0.72) SIGLEC7MAGSELLSELPSELE
SCHEMBL17897302 0.90 SIGLEC7 (0.72) SIGLEC7MAGSELLSELPSELE
SCHEMBL16381196 0.90 SIGLEC7 (0.72) SIGLEC7MAGSELLSELPSELE
SCHEMBL17897337 0.90 SIGLEC7 (0.72) SIGLEC7MAGSELLSELPSELE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9221879-B2 Multiligand constructs SEMIOTIK LLC (RU) 2015-12-29 — — US disclosed
US-20140135477-A1 MULTILIGAND CONSTRUCTS SEMIOTIK LLC (RU) 2014-05-15 — — US disclosed
US-8674061-B2 Multiligand constructs Smiotik LLC (RU) 2014-03-18 — — US disclosed
US-20110257081-A1 MULTIGAND CONSTRUCTS SEMIOTIK LLC (RU) 2011-10-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110257081-A1 MULTIGAND CONSTRUCTS KLK3, PAICS, BTD SIGLEC7 135/4885MAG 148/4885SELL 807/4885
US-20140135477-A1 MULTILIGAND CONSTRUCTS KLK3, CD2BP2, PAICS SIGLEC7 137/4885MAG 214/4885SELL 369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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