Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 16/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 13/20 | 0.59 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.59 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.58 |
| ▸ | PIK3R1 | P27986 | 7/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12233 | 0.94 | PIK3CD (0.63) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL12079 | 0.90 | PIK3CD (0.69) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL12147 | 0.89 | PIK3CD (0.64) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL12057 | 0.88 | PIK3CD (0.74) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL11505 | 0.88 | PIK3CD (0.76) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL31655842 | 0.88 | PIK3CD (0.76) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL11985 | 0.85 | PIK3CD (0.77) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL12257 | 0.84 | PIK3CD (0.56) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL12097 | 0.83 | PIK3CD (0.65) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL11872 | 0.83 | PIK3CD (0.65) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2491037-A1 | COMPOUNDS | Respivert Limited (GB) | 2012-08-29 | — | — | EP | disclosed |
| WO-2011048111-A1 | COMPOUNDS | RESPIVERT LIMITED (GB) | 2011-04-28 | — | — | WO | disclosed |