Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10091424 | 0.96 | SMN1; SMN2 (0.35) | SMN1; SMN2ACACBHPGDMAPTGLA | |
| SCHEMBL12223965 | 0.94 | SMN1; SMN2 (0.33) | SMN1; SMN2ACACBHPGDGLA | |
| SCHEMBL12224656 | 0.93 | SMN1; SMN2 (0.34) | SMN1; SMN2ACACBHPGDMAPTPTGS1 | |
| SCHEMBL11939136 | 0.92 | HPGD (0.37) | SMN1; SMN2ACACBHPGDALOX5APFEN1 | |
| SCHEMBL11939255 | 0.92 | HPGD (0.37) | SMN1; SMN2ACACBHPGDALOX5APFEN1 | |
| SCHEMBL12223568 | 0.91 | TYR (0.31) | — | |
| SCHEMBL12222963 | 0.91 | TYR (0.31) | — | |
| SCHEMBL12222960 | 0.90 | SMN1; SMN2 (0.34) | SMN1; SMN2ACACBHPGDMAPTPTGS1 | |
| SCHEMBL14922583 | 0.89 | SMN1; SMN2 (0.39) | SMN1; SMN2ACACBHPGDMAPTPTGS1 | |
| SCHEMBL14922599 | 0.89 | SMN1; SMN2 (0.39) | SMN1; SMN2ACACBHPGDMAPTPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110240919-A1 | FIVE-RING COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110240919-A1 | FIVE-RING COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | NCAPD3, CCND3, ZKSCAN2 | SMN1; SMN2 3764/4885ACACB 2691/4885HPGD 4261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.