SCHEMBL122433

SCHEMBL122433

C1NCOCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18594791 0.96
SCHEMBL11666924 0.96
SCHEMBL1652731 0.80
SCHEMBL14576424 0.75
SCHEMBL11734314 0.73
Oxazolidine SCHEMBL3381804 0.66 KDM4E (0.53)
SCHEMBL17030391 0.64
SCHEMBL2115735 0.64
SCHEMBL44386 0.61
SCHEMBL17366418 0.61 HIF1A (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 782 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023090779-A1 ANTIMICROBIAL 3D PRINTING COMPOSITION AND ANTIMICROBIAL 3D-PRINTED DENTAL PRODUCT USING SAME (주) 베리콤 2023-05-25 WO claimed
CN-113861128-A Polymerizable compound and optically anisotropic body 江苏创拓新材料有限公司 2021-12-31 CN claimed
CN-109180604-A A kind of production method of 3- methyl -4- nitro-imine base tetrahydro -1,3,5- oxadiazines 浙江中山化工集团股份有限公司 2019-01-11 CN claimed
CN-105622541-A Synthesis method of 3-methyl-4-nitroiminoperhydro-1,3,5-oxadiazine KAMP PHARMACEUTICALS CO LTD 2016-06-01 CN claimed
EP-2520568-B1 Spirocyclic nitriles as inhibitors of protease SANOFI SA (FR) 2015-09-09 EP claimed
CN-103613560-B Synthetic method for 3-methyl-4-nitroiminoperhydro-1,3,5-oxadiazine NANTONG TENDENCI CHEMICAL CO 2015-01-07 CN claimed
CN-103613560-A Synthetic method for 3-methyl-4-nitroiminoperhydro-1,3,5-oxadiazine NANTONG TENDENCI CHEMICAL CO 2014-03-05 CN claimed
US-8609681-B2 Spirocyclic nitriles as protease inhibitors SANOFI (FR) 2013-12-17 US claimed
EP-2520568-A1 Spirocyclic nitriles as inhibitors of protease SANOFI (FR) 2012-11-07 EP claimed
EP-1852420-B1 Indole compounds for treating respiratory disorders ONO PHARMACEUTICAL CO (JP) 2012-10-17 EP claimed
US-20060127348-A1 Chemically and/or biologically reactive compounds ISOTRON CORPORATION (US) 2006-06-15 US claimed
WO-2003092656-A1 CHEMICALLY AND/OR BIOLOGICALLY REACTIVE COMPOUDS ISOTRON CORPORATION (US) 2003-11-13 WO claimed
US-5696154-A ANTITUMOR AGENTS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1997-12-09 US claimed
EP-0767788-A1 NEW BREFELDIN A DERIVATIVES AND THEIR UTILITY IN THE TREATMENT OF CANCER THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1997-04-16 EP claimed
WO-1996000726-A2 NEW BREFELDIN A DERIVATIVES AND THEIR UTILITY IN THE TREATMENT OF CANCER THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1996-01-11 WO claimed
EP-0341322-B1 Polyether end-blocked with hydrolyzable silyl groups, method of manufacturing and room temperature curable composition using the polyether TOSHIBA SILICONE (JP) 1993-12-22 EP claimed
US-5061739-A SEALANTS FOR CONSTRUCTION TOSHIBA SILICONE CO., LTD. (JP) 1991-10-29 US claimed
EP-0341322-A1 Polyether end-blocked with hydrolyzable silyl groups, method of manufacturing and room temperature curable composition using the polyether TOSHIBA SILICONE COMPANY, LTD. (JP) 1989-11-15 EP claimed
US-4873272-A Polyether end-blocked with hydrolyzable silyl groups, method of manufacturing and room temperature curable composition using the polyether TOSHIBA SILICONE CO., LTD. (JP) 1989-10-10 US claimed
US-4228310-A FOR POLYISOCYANURATE TEXACO DEVELOPMENT CORP. (US) 1980-10-14 US claimed