Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.82 |
| ▸ | PIK3CG | P48736 | 13/20 | 0.82 |
| ▸ | PIK3R1 | P27986 | 11/20 | 0.82 |
| ▸ | PIK3CB | P42338 | 11/20 | 0.82 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.52 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2509499 | 0.90 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL12264116 | 0.84 | PIK3CD (0.79) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL12264115 | 0.81 | PIK3CD (0.70) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL12263268 | 0.78 | PIK3CD (0.80) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL2508335 | 0.76 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL2511207 | 0.76 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL2508310 | 0.74 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL2507674 | 0.74 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL2507074 | 0.73 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL2505314 | 0.73 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123751-A2 | HETEROCYCLIC COMPOUNDS AND THEIR USES | AMGEN INC. (US) | 2011-10-06 | — | — | WO | disclosed |