Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RYR2 | Q92736 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807004 | 0.85 | RYR2 (1.00) | RYR2 | |
| SCHEMBL807006 | 0.85 | RYR2 (1.00) | RYR2 | |
| SCHEMBL6867569 | 0.78 | RYR2 (0.82) | RYR2 | |
| SCHEMBL807008 | 0.78 | RYR2 (1.00) | RYR2 | |
| SCHEMBL6867710 | 0.77 | RYR2 (1.00) | RYR2 | |
| SCHEMBL12265307 | 0.77 | RYR2 (0.88) | RYR2 | |
| SCHEMBL12313213 | 0.76 | RYR2 (0.86) | RYR2 | |
| SCHEMBL6867723 | 0.76 | RYR2 (0.86) | RYR2 | |
| SCHEMBL3428542 | 0.76 | RYR2 (0.77) | RYR2 | |
| SCHEMBL6867412 | 0.75 | RYR2 (0.85) | RYR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022058-B2 | Agents for preventing and treating disorders involving modulation of the RyR receptors | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2011-09-20 | — | — | US | disclosed |