SCHEMBL12281973

SCHEMBL12281973

O=P(O)(OC[C@H](O)COP(=O)(O)OC[C@H](O)COP(=O)(O)OC[C@H](O)CO)OC[C@@H](O)COP(=O)(O)OC[C@@H](O)CO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.44
SELP P16109 1/20 0.39
P2RY10 O00398 7/20 0.38
GPR174 Q9BXC1 6/20 0.38
GPR34 Q9UPC5 5/20 0.38
LPAR5 Q9H1C0 2/20 0.38
LMNA P02545 2/20 0.36
ALDH1A1 P00352 1/20 0.36
PGK1 P00558 1/20 0.35
PGK2 P07205 1/20 0.35
LPAR6 P43657 1/20 0.35
LPAR1 Q92633 1/20 0.35
LPAR4 Q99677 1/20 0.35
LPAR2 Q9HBW0 1/20 0.35
LPAR3 Q9UBY5 1/20 0.35
ENPP2 Q13822 1/20 0.35
GPR55 Q9Y2T6 1/20 0.34
MPI P34949 1/20 0.33
PGD P52209 1/20 0.33
P2RY2 P41231 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12283190 1.00 SMN1; SMN2 (0.44) SMN1; SMN2SELPP2RY10GPR174GPR34
SCHEMBL12282496 1.00 SMN1; SMN2 (0.44) SMN1; SMN2SELPP2RY10GPR174GPR34
SCHEMBL24111174 1.00 SMN1; SMN2 (0.44) SMN1; SMN2SELPP2RY10GPR174GPR34
SCHEMBL12284729 0.98 SMN1; SMN2 (0.46) SMN1; SMN2SELPP2RY10GPR174GPR34
SCHEMBL30148756 0.98 SMN1; SMN2 (0.46) SMN1; SMN2SELPP2RY10GPR174GPR34
SCHEMBL579431 0.98 SMN1; SMN2 (0.46) SMN1; SMN2SELPP2RY10GPR174GPR34
SCHEMBL29708086 0.98 SMN1; SMN2 (0.46) SMN1; SMN2SELPP2RY10GPR174GPR34
SCHEMBL17513028 0.95 SMN1; SMN2 (0.44) SMN1; SMN2SELPP2RY10GPR174GPR34
SCHEMBL30244880 0.95 SMN1; SMN2 (0.49) SMN1; SMN2SELPP2RY10GPR174GPR34
SCHEMBL12284731 0.94 LPAR5 (0.46) SMN1; SMN2LPAR5PGK1PGK2LPAR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2574237-A1 Use of a lipoteichoic acid, mono- or polyglycerophosphate for antibacterial pre-treatment and especially in medical devices Lunamed AG (CH) 2013-04-03 EP disclosed
WO-2011120707-A1 COMPOSITIONS FOR DENTAL TREATMENT COMPRISING LIPOTEICHOIC ACIDS OR PARTS THEREOF LIKE MONO- OR POLYGLYCERPHOSPHATES LUNAMED AG (CH) 2011-10-06 WO disclosed