Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16852214 | 0.74 | HDAC6 (0.50) | HDAC6HDAC1HDAC8HDAC3HDAC7 | |
| SCHEMBL12210564 | 0.66 | HDAC6 (0.52) | HDAC6HDAC1HDAC8HDAC3HDAC7 | |
| SCHEMBL12286460 | 0.66 | HDAC6 (0.57) | HDAC6HDAC1HDAC8HDAC3HDAC7 | |
| SCHEMBL2522000 | 0.63 | HDAC6 (0.50) | HDAC6HDAC1HDAC8HDAC3HDAC7 | |
| SCHEMBL12210528 | 0.63 | HDAC6 (0.60) | HDAC6HDAC1HDAC8HDAC3HDAC7 | |
| SCHEMBL12283183 | 0.62 | HDAC6 (0.57) | HDAC6HDAC1HDAC8HDAC3HDAC7 | |
| SCHEMBL12211139 | 0.61 | HDAC6 (0.49) | HDAC6HDAC1HDAC8HDAC3HDAC7 | |
| SCHEMBL12210539 | 0.61 | HDAC6 (0.66) | HDAC6HDAC1HDAC8HDAC3HDAC7 | |
| SCHEMBL12210497 | 0.61 | HDAC6 (0.62) | HDAC6HDAC1HDAC8HDAC3HDAC7 | |
| SCHEMBL12211171 | 0.60 | HDAC6 (0.54) | HDAC6HDAC1HDAC8HDAC3HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011130163-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-10-20 | — | — | WO | disclosed |