Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 8/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SLC7A11 | Q9UPY5 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.56 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11421910 | 0.89 | SLC7A11 (0.64) | BRD4ALDH1A1SLC7A11LMNAMEN1 | |
| Sulfasalazine SCHEMBL27891148 | 0.73 | SLC7A11 (0.79) | BRD4ALDH1A1SLC7A11LMNAMEN1 | |
| SCHEMBL32662838 | 0.72 | SLC7A11 (0.71) | BRD4ALDH1A1SLC7A11LMNAMEN1 | |
| SCHEMBL6885835 | 0.72 | KDM4E (0.50) | ALDH1A1LMNAMEN1KMT2AUSP2 | |
| SCHEMBL10794987 | 0.72 | KMT2A (0.46) | ALDH1A1LMNAMEN1KMT2AUSP2 | |
| Sulfasalazine SCHEMBL10289061 | 0.72 | SLC7A11 (1.00) | BRD4ALDH1A1SLC7A11LMNAMEN1 | |
| Sulfasalazine SCHEMBL5664970 | 0.72 | SLC7A11 (1.00) | BRD4ALDH1A1SLC7A11LMNAMEN1 | |
| Sulfasalazine SCHEMBL4514 | 0.72 | SLC7A11 (1.00) | BRD4ALDH1A1SLC7A11LMNAMEN1 | |
| Sulfasalazine SCHEMBL487664 | 0.72 | SLC7A11 (1.00) | BRD4ALDH1A1SLC7A11LMNAMEN1 | |
| Sulfasalazine SCHEMBL4515 | 0.72 | SLC7A11 (1.00) | BRD4ALDH1A1SLC7A11LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7881871-B2 | Method for designing surfaces | BIO-LAYER PTY LIMITED (AU) | 2011-02-01 | — | — | US | claimed |
| US-20070099235-A1 | Method for designing surfaces | BIO-LAYER PTY LIMITED (AU) | 2007-05-03 | — | — | US | claimed |